Ivermectin for Prevention and Treatment of COVID-19 Infection
A Systematic Review, Meta-analysis, and Trial Sequential Analysis to Inform Clinical Guidelines
Abstract
Background:
Repurposed medicines may have a role against the SARS-CoV-2 virus. The antiparasitic ivermectin, with antiviral and anti-inflammatory properties, has now been tested in numerous clinical trials.
Areas of uncertainty:
We assessed the efficacy of ivermectin treatment in reducing mortality, in secondary outcomes, and in chemoprophylaxis, among people with, or at high risk of, COVID-19 infection.
Data sources:
We searched bibliographic databases up to April 25, 2021. Two review authors sifted for studies, extracted data, and assessed risk of bias. Meta-analyses were conducted and certainty of the evidence was assessed using the GRADE approach and additionally in trial sequential analyses for mortality. Twenty-four randomized controlled trials involving 3406 participants met review inclusion.
Therapeutic Advances:
Meta-analysis of 15 trials found that ivermectin reduced risk of death compared with no ivermectin (average risk ratio 0.38, 95% confidence interval 0.19–0.73; n = 2438; I2 = 49%; moderate-certainty evidence). This result was confirmed in a trial sequential analysis using the same DerSimonian–Laird method that underpinned the unadjusted analysis. This was also robust against a trial sequential analysis using the Biggerstaff–Tweedie method. Low-certainty evidence found that ivermectin prophylaxis reduced COVID-19 infection by an average 86% (95% confidence interval 79%–91%). Secondary outcomes provided less certain evidence. Low-certainty evidence suggested that there may be no benefit with ivermectin for “need for mechanical ventilation,” whereas effect estimates for “improvement” and “deterioration” clearly favored ivermectin use. Severe adverse events were rare among treatment trials and evidence of no difference was assessed as low certainty. Evidence on other secondary outcomes was very low certainty.
Conclusions:
Moderate-certainty evidence finds that large reductions in COVID-19 deaths are possible using ivermectin. Using ivermectin early in the clinical course may reduce numbers progressing to severe disease. The apparent safety and low cost suggest that ivermectin is likely to have a significant impact on the SARS-CoV-2 pandemic globally.
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The Time for Silence is Over
A unified pushback against the globalist agenda
It’s finally here, the Global Walkout begins September 4th at 8pm London time and continue every weeks. Next step 4th June 2023.
One step at a time, hand in hand, we are walking out from the globalist society they are trying to enslave us into
ANYONE can participate
ANYWHERE in the world
JOIN or read about it here – https://globalwalkout.com
https://www.reignitefreedom.com/
The third step is to unsubscribe from all mainstream media outlets. Delete the apps from your phone, laptop, and tablet and unfollow all of their social media and YouTube channels. Try to avoid mainstream media for at least one week, even if the headline is intriguing.
In the same time why not removing all the big tech tracking/spying/social credit system around you: (Youtube, Facebook, Instagram, Twitter, Tik Tok, Google, Apple, Microsoft, Whatsapp, Zoom, Linkedln, Snapchat, Tumblr, Pinterest, Reddit, Myspace, etc.)
The fourth step of the global walkout is to move as many accounts as you can to a union or local bank.
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If you are looking for solutions (lawyer, form, gathering, action, antidote, treatments, maybe this could help you:
HERE
If you want to fight back better:
https://childrenshealthdefense.org/child-health-topics/health-freedom/defender-days-sticker-gallery/
Find the others: www.freedomcells.org
Spike Protein Protocol
Glutathione (most important for body detoxification) or better
NAC = N-Acetyl-Cysteine 600-750mg (causes the body to produce glutathione itself)
Zinc
Astaxantin 5mg (also improves vision)
Quercetin
vitamin D3
Milk thistle (also liver and stomach protection)
Melatonin 1mg to 10mg (against 5G)
Alternatively CDS/CDL and zeolite
Dr. Zelenko’s Protocol contains Ivermectin, Hydroxychloroquine (HCQ), Zinc, Vitamin D3, and Quercetin.
How to find the truth :
Search engine: https://presearch.org/, https://search.brave.com/, Searx (choose the server that you want) or https://metager.org/
Videos: www.odysee.com
www.bitchute.com
www.brandnewtube.com
Facebook style: www.gab.com or https://www.minds.com/
INTELLIGENCE ISN’T KNOWING EVERYTHING, IT’S THE ABILITY TO CHALLENGE EVERYTHING YOU KNOW
Rights and Freedoms 