New research found that natural immunity offers exponentially more protection than COVID-19 vaccines.
Monday, August 30, 2021
Photo by Thérèse Soukar, CC BY-SA 4.0 , via Wikimedia Commons
Anewly published medical study found that infection from COVID-19 confers considerably longer-lasting and stronger protection against the Delta variant of the virus than vaccines.
“The natural immune protection that develops after a SARS-CoV-2 infection offers considerably more of a shield against the Delta variant of the pandemic coronavirus than two doses of the Pfizer-BioNTech vaccine, according to a large Israeli study that some scientists wish came with a ‘Don’t try this at home’ label,” the Scientific American reported Thursday. “The newly released data show people who once had a SARS-CoV-2 infection were much less likely than vaccinated people to get Delta, develop symptoms from it, or become hospitalized with serious COVID-19.”
Put another way, vaccinated individuals were 27 times more likely to get a symptomatic COVID infection than those with natural immunity from COVID.
A Death Blow to Vaccine Passports?
The findings come as many governments around the world are demanding citizens acquire “vaccine passports” to travel. New York City, France, and the Canadian provinces of Quebec and British Columbia are among those who have recently embraced vaccine passports.
Meanwhile, Australia has floated the idea of making higher vaccination rates a condition of lifting its lockdown in jurisdictions, while President Joe Biden is considering making interstate travel unlawful for people who have not been vaccinated for COVID-19.
Vaccine passports are morally dubious for many reasons, not the least of which is that freedom of movement is a basic human right. However, vaccine passports become even more senseless in light of the new findings out of Israel and revelations from the CDC, some say.
Harvard Medical School professor Martin Kulldorff said research showing that natural immunity offers exponentially more protection than vaccines means vaccine passports are both unscientific and discriminatory, since they disproportionately affect working class individuals.
“Prior COVID disease (many working class) provides better immunity than vaccines (many professionals), so vaccine mandates are not only scientific nonsense, they are also discriminatory and unethical,” Kulldorff, a biostatistician and epidemiologist, observed on Twitter.
Nor is the study out of Israel a one-off. Media reports show that no fewer than 15 academic studies have found that natural immunity offers immense protection from COVID-19.
Moreover, CDC research shows that vaccinated individuals still get infected with COVID-19 and carry just as much of the virus in their throat and nasal passage as unvaccinated individuals
“High viral loads suggest an increased risk of transmission and raised concern that, unlike with other variants, vaccinated people infected with Delta can transmit the virus,” CDC Rochelle Director Walensky noted following a Cape Cod outbreak that included mostly vaccinated individuals.
These data suggest that vaccinated individuals are still spreading the virus much like unvaccinated individuals.
The Bottom Line
Vaccine passports would be immoral and a massive government overreach even in the absence of these findings. There is simply no historical parallel for governments attempting to restrict the movements of healthy people over a respiratory virus in this manner.
Yet the justification for vaccine passports becomes not just wrong but absurd in light of these new revelations.
People who have had COVID already have significantly more protection from the virus than people who’ve been vaccinated. Meanwhile, people who’ve not had COVID and choose to not get vaccinated may or may not be making an unwise decision. But if they are, they are principally putting only themselves at risk.
Jonathan Miltimore is the Managing Editor of FEE.org. His writing/reporting has been the subject of articles in TIME magazine, The Wall Street Journal, CNN, Forbes, Fox News, and the Star Tribune.
Bylines: Newsweek, The Washington Times, MSN.com, The Washington Examiner, The Daily Caller, The Federalist, the Epoch Times.
Comparing SARS-CoV-2 natural immunity to vaccine-induced immunity: reinfections versus breakthrough infections
Sivan Gazit, Roei Shlezinger, Galit Perez, Roni Lotan, Asaf Peretz, Amir Ben-Tov, Dani Cohen, Khitam Muhsen, Gabriel Chodick, Tal Patalondoi: https://doi.org/10.1101/2021.08.24.21262415This article is a preprint and has not been peer-reviewed [what does this mean?]. It reports new medical research that has yet to be evaluated and so should not be used to guide clinical practice.
Background Reports of waning vaccine-induced immunity against COVID-19 have begun to surface. With that, the comparable long-term protection conferred by previous infection with SARS-CoV-2 remains unclear.
Methods We conducted a retrospective observational study comparing three groups: (1)SARS-CoV-2-naïve individuals who received a two-dose regimen of the BioNTech/Pfizer mRNA BNT162b2 vaccine, (2)previously infected individuals who have not been vaccinated, and (3)previously infected and single dose vaccinated individuals. Three multivariate logistic regression models were applied. In all models we evaluated four outcomes: SARS-CoV-2 infection, symptomatic disease, COVID-19-related hospitalization and death. The follow-up period of June 1 to August 14, 2021, when the Delta variant was dominant in Israel.
Results SARS-CoV-2-naïve vaccinees had a 13.06-fold (95% CI, 8.08 to 21.11) increased risk for breakthrough infection with the Delta variant compared to those previously infected, when the first event (infection or vaccination) occurred during January and February of 2021. The increased risk was significant (P<0.001) for symptomatic disease as well. When allowing the infection to occur at any time before vaccination (from March 2020 to February 2021), evidence of waning natural immunity was demonstrated, though SARS-CoV-2 naïve vaccinees had a 5.96-fold (95% CI, 4.85 to 7.33) increased risk for breakthrough infection and a 7.13-fold (95% CI, 5.51 to 9.21) increased risk for symptomatic disease. SARS-CoV-2-naïve vaccinees were also at a greater risk for COVID-19-related-hospitalizations compared to those that were previously infected.
Conclusions This study demonstrated that natural immunity confers longer lasting and stronger protection against infection, symptomatic disease and hospitalization caused by the Delta variant of SARS-CoV-2, compared to the BNT162b2 two-dose vaccine-induced immunity. Individuals who were both previously infected with SARS-CoV-2 and given a single dose of the vaccine gained additional protection against the Delta variant.
Competing Interest Statement
The authors have declared no competing interest.
There was no external funding for the project.
I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.
The details of the IRB/oversight body that provided approval or exemption for the research described are given below:
This study was approved by the MHS (Maccabi Healthcare Services) Institutional Review Board (IRB). Due to the retrospective design of the study, informed consent was waived by the IRB, and all identifying details of the participants were removed before computational analysis.
All necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived.
I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance).
I have followed all appropriate research reporting guidelines and uploaded the relevant EQUATOR Network research reporting checklist(s) and other pertinent material as supplementary files, if applicable.
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