EMA Investigates Three Possible New Side Effects of Pfizer and Moderna Vaccines

These are erythema multiforme, glomerulonephritis and nephrotic syndrome, according to the European Medicines Agency
Why does the second dose of the Pfizer and Moderna vaccines give more side effects?

EP Updated:08/18/2021 KEEP168


The Safety Committee (PRAC) of the European Medicines Agency ( EMA ) is investigating three possible new adverse effects of mRNA vaccines against Covid-19 , that is, those developed by Pfizer and Moderna.

Specifically, as detailed by the European regulatory body in vaccine safety update documents, it is erythema multiforme, glomerulonephritis and nephrotic syndrome .

Erythema multiforme is an allergic hypersensitivity reaction with characteristic round skin lesions that can also affect the mucous membranes of the internal cavities of the body. The EMA has recorded “a small number of cases” reported after vaccination with Pfizer and Moderna. “More data and analysis have been requested from the marketing authorization holder to support the ongoing evaluation of the PRAC,” explains the European regulatory body.

For its part, an evaluation of glomerulonephritis ( inflammation of the tiny filters of the kidneys ) and nephrotic syndrome ( kidney disorder that causes the kidneys to lose too much protein in the urine ) has been started to determine if they may be side effects of these two vaccines.

According to the EMA, affected patients may present with bloody or foamy urine, edema (swelling of the eyelids, feet or abdomen) or fatigue . As in the previous case, there have been ‘a small number of cases’ reported after vaccination with Pfizer and Moderna, including cases in which patients experienced a relapse of pre-existing kidney disease. Therefore, more data and analysis have also been requested from the companies to continue with the evaluation.

As the EMA explained last week, it has not found “so far” any causal association between Covid-19 vaccines and menstrual disorders. The European regulatory body emphasizes that menstrual disorders are “very common and can occur without an underlying medical condition.”

“The causes can range from stress and fatigue to underlying medical conditions, such as fibroids and endometriosis . Women who experience unexpected vaginal bleeding (for example, in postmenopausal women) or who are concerned about prolonged or severe menstrual disturbances can seek medical advice, they rivet.



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